There is some confusion about the specific antibodies that make up antiphospholipid antibodies (aPL). Can you specify which antibodies we should be looking for? (UKMEC 2016)

Rheumatic diseases


The antibodies are lupus anticoagulant and anticardiolipin antibodies. Lupus anticoagulant is either positive or negative. Anticardiolipin antibodies are given as a value, the higher the result the more likely it is to be clinically significant. It is less specific but can offer a guide for further investigations or referral to haematology. Tests must be repeated after 12 weeks as one result is not confirmatory.

You may also find this link to Arthritis Research UK website useful.  (accessed 26/05/2016)

For further information regarding the diagnosis of APS, please refer to the International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS).  (accessed 26/05/2016)

View the UKMEC.